PharmacyCodes



Isradipino [Spanish] en es it fr

Categorie

Isradipino [Spanish] Les marques, Isradipino [Spanish] Analogs

Isradipino [Spanish] Les marques melange

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    • Isradipino [Spanish] Formule chimique

    C19H21N3O5

    Isradipino [Spanish] RX lien

    http://www.rxlist.com/cgi/generic2/israd.htm

    Isradipino [Spanish] FDA fiche

    Isradipino [Spanish] msds (fiche de securite des materiaux)

    Isradipino_[Spanish] MSDS

    Isradipino [Spanish] Synthese de reference

    P. Neumann, le brevet américain. 4,466,972 (1984)

    Isradipino [Spanish] Poids moleculaire

    371.387 g/mol

    Isradipino [Spanish] Point de fusion

    168-170 oC

    Isradipino [Spanish] H2O Solubilite

    Pratiquement insoluble (<10 mg / L à 37 ° C)

    Isradipino [Spanish] Etat

    Solid

    Isradipino [Spanish] LogP

    2.901

    Isradipino [Spanish] Formes pharmaceutiques

    Capsules (2,5 mg ou 5 mg)

    Isradipino [Spanish] Indication

    Pour la gestion de l'hypertension. Il peut être utilisé seul ou conjointement avec des diurétiques thiazidiques.

    Isradipino [Spanish] Pharmacologie

    Isradipine, le plus puissant des canaux calciques agent bloquant de la classe des dihydropyridines, est similaire à la nifédipine, l'amlodipine et la félodipine. Il se lie aux canaux calciques avec une haute affinité et spécificité et inhibe le flux de calcium dans le muscle cardiaque et lisse. Les effets observés dans des expériences in vitro et mécanistiques étudiées chez les animaux intacts et l'homme sont compatibles avec ce mécanisme d'action et sont typiques de la classe.

    Isradipino [Spanish] Absorption

    Isradipine est de 90% -95% absorbée et est soumise à un effet de premier passage hépatique, résultant en une biodisponibilité d'environ 15% -24%.

    Isradipino [Spanish] Toxicite

    Les symptômes de surdose comprennent la léthargie, la tachycardie sinusale et une hypotension transitoire. Létalité importante a été observée chez les souris ayant reçu des doses orales de plus de 200 mg / kg et des lapins ayant reçu environ 50 mg / kg de l'isradipine. Les rats ont toléré des doses de plus de 2000 mg / kg sans effet sur la survie.

    Isradipino [Spanish] Information pour les patients

    Description
    --------------------------------------------------------------------------------

    For those patients who have high blood pressure, and is sometime used to treat angina
    (chest pains).

    General Information
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    This information is for educational purposes only. Not every known side effect, adverse
    effect, or drug interaction is in this database. If you have questions about your medicines,
    talk to your healthcare provider.

    Proper use of this medicine
    --------------------------------------------------------------------------------

    Take this medicine exactly as directed. This medicine is normally taken once daily. It is
    taken orally and may be taken with or without food. The extended-release tablet and capsule
    should be swallowed whole. Do not chew, divide, or crush the extended-release tablet or
    capsule.


    Missed Dose
    --------------------------------------------------------------------------------

    Take your next dose as soon as you remember. If it is time for your next dose, skip the
    missed dose and go back to your regular schedule. Do not double doses.


    Storage
    --------------------------------------------------------------------------------

    Keep this medication in the container it came in, tightly closed, and out of reach of
    children. Store it at room temperature and away from excess heat and moisture. Throw away
    any medication that is outdated or no longer needed.


    Possible Side Effects
    --------------------------------------------------------------------------------

    If you experience other bothersome side effects, contact your health care provider.
    Some common side effects reported with this medicine include:
    nausea
    dizziness
    headache
    swelling


    Warnings/Precautions
    --------------------------------------------------------------------------------

    Do not stop suddenly stop this medicine without talking to your doctor.
    This medicine can cause dizziness. Use caution when operating a motor vehicle.


    Overdose
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    Seek medical attention immediately. For non emergencies, contact your local or regional
    poison control center


    Drug Interactions
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    Tell your doctor and pharmacist about all other medicines that you are taking, including
    non-prescription medicines, nutritional supplements, or herbal products.


    Pregnancy/Nursing
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    If you suspect that you may be pregnant, talk to your doctor. There are no clear answers,
    but animal studies suggest caution during pregnancy, and use should only be when risks are
    outweighed by possible benefits. For nursing mothers, it is not known if amlodipine is
    excreted in breast milk, so caution is recommended.


    More Information
    --------------------------------------------------------------------------------

    For more information about this medicine, talk to your healthcare provider.

    Isradipino [Spanish] Organismes affectes

    Les humains et autres mammifères